other material
confidence high
sentiment positive
materiality 0.85
Cognition Therapeutics: oral zervimesine cuts GA lesion growth 28.6% in Phase 2 trial
COGNITION THERAPEUTICS INC
- Zervimesine-treated patients had 28.6% slower GA lesion growth rate vs placebo in Phase 2 MAGNIFY study.
- At 18 months, mean lesion size was 28.2% smaller for zervimesine group compared to placebo.
- Trial concluded early with ~100 of planned 246 enrolled; company focuses resources on Alzheimer's and DLB programs.
- Dry AMD is third indication where zervimesine showed efficacy signals; oral pill vs current injectable treatments.
- Additional safety, demographic, and visual outcome data still being analyzed; results to be presented at medical meeting.