other material
confidence high
sentiment positive
materiality 0.85
Armata's AP-SA02 shows 100% clinical response in Phase 1b/2a S. aureus bacteremia trial
Armata Pharmaceuticals, Inc.
- Primary endpoints met: safety, tolerability, and clinical response in ITT (n=50).
- AP-SA02 + BAT achieved 100% clinical response at TOC for BAT and EOS vs 75% for placebo (p=0.017).
- No treatment-related serious adverse events; two possibly related events (liver enzyme elevation, hypersensitivity).
- At day 12, responder rate 88% AP-SA02 vs 58% placebo (p=0.047); MRSA patients had no relapse.
- Company plans to initiate a pivotal trial as rapidly as possible.