{"schema_version":"secwatch.filing_event.v1","accession":"0001104659-25-050771","form_type":"8-K","ticker":"MRKR","cik":"0001094038","company_name":"Marker Therapeutics, Inc.","filed_at":"2025-05-20T23:59:59+00:00","discovered_at":"2026-05-14T18:02:47.494502+00:00","generated_at":"2026-05-20T23:34:45.642485+00:00","sec_items":["8.01","9.01"],"event_type":"other_material","sentiment":"positive","materiality_score":0.65,"calibrated_materiality_score":0.65,"confidence":"high","headline":"Marker Therapeutics: lymphodepletion improves MT-601 cell expansion; enrollment surging","bullets":["Phase 1 APOLLO study data: TCR sequencing shows MT-601 clones expanded/persisted at higher levels with lymphodepletion.","Prior data (Dec 2024): 7/9 patients (78%) objective response, 4 complete responses (44.4%); no DLTs or ICANS.","In first 5 months of 2025, enrolled and manufactured product for more patients than in all of 2024.","Company expects clinical data readout from APOLLO study later this year.","MT-601 targets lymphoma patients who relapsed after anti-CD19 CAR-T or for whom CAR-T is not an option."],"urls":{"canonical":"https://secwatch.observer/filing/0001104659-25-050771","json":"https://secwatch.observer/filing/0001104659-25-050771.json","markdown":"https://secwatch.observer/filing/0001104659-25-050771.md","text":"https://secwatch.observer/filing/0001104659-25-050771.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1094038/000110465925050771/0001104659-25-050771-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1094038/000110465925050771/tm2515620d1_8k.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-05-20T23:34:45.642485+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}