secwatch.observer — SEC 8-K summary ====================================== Issuer: Annovis Bio, Inc. (ANVS) CIK: 0001477845 Form: 8-K Filed at: 2025-08-12T23:59:59+00:00 Accession: 0001104659-25-076851 Event type: earnings Sentiment: positive Materiality: 0.65 Item codes: 2.02, 9.01 LLM model: deepseek-v4-flash:cloud@v2 Annovis Bio Q2 net loss $0.32/sh; cash $17.1M; Phase 3 AD trial advances with 38 patients randomized -------------------------------------------------------------------------------- - Cash and cash equivalents $17.1M as of June 30, 2025, up from $10.6M at Dec 31, 2024. - Net loss per share $0.32 (basic/diluted) for Q2 2025 vs $0.44 in Q2 2024. - Phase 3 early AD trial: 38 patients randomized, nearly 200 in screening, 76 U.S. sites (46 enrolling). - R&D expenses $5.2M, G&A $1.1M, both down YoY. - Transferred all patent families to crystal buntanetap, achieving comprehensive global IP coverage. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1477845/000110465925076851/0001104659-25-076851-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1477845/000110465925076851/tm2523281d1_8k.htm HTML page: https://secwatch.observer/filing/0001104659-25-076851 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer