---
schema_version: "secwatch.filing_event.v1"
accession: "0001104659-25-087865"
form_type: "8-K"
ticker: "PRAX"
cik: "0001689548"
company_name: "Praxis Precision Medicines, Inc."
filed_at: "2025-09-05T23:59:59+00:00"
generated_at: "2026-05-17T07:59:04.957443+00:00"
event_type: "other_material"
sentiment: "neutral"
materiality_score: 0.6
calibrated_materiality_score: 0.6
confidence: "high"
source: SEC EDGAR
---

# Praxis terminates $250M Jefferies ATM, enters new $250M ATM with TD Cowen

## Summary
- Terminated 2024 Sales Agreement with Jefferies effective Sept 2, 2025; no penalties.
- Previously sold 1,368,176 shares for ~$86.2M gross proceeds under that agreement.
- Entered new 2025 Sales Agreement with TD Cowen for up to $250M in at-the-market offerings.
- TD Cowen will receive a commission of up to 3.0% of gross proceeds from sales.
- New ATM will be made under existing S-3ASR registration statement.

## SEC filing metadata
- accession: 0001104659-25-087865
- form_type: 8-K
- ticker: PRAX
- cik: 0001689548
- company_name: Praxis Precision Medicines, Inc.
- filed_at: 2025-09-05T23:59:59+00:00
- event_type: other_material
- sentiment: neutral
- materiality_score: 0.6
- calibrated_materiality_score: 0.6
- confidence: high
- sec_items: 8.01, 9.01
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1689548/000110465925087865/0001104659-25-087865-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1689548/000110465925087865/tm2525240d2_8k.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0001104659-25-087865
- JSON: https://secwatch.observer/filing/0001104659-25-087865.json
- Plain text: https://secwatch.observer/filing/0001104659-25-087865.txt

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.