{"schema_version":"secwatch.filing_event.v1","accession":"0001104659-25-088021","form_type":"8-K","ticker":"VSTM","cik":"0001526119","company_name":"Verastem, Inc.","filed_at":"2025-09-08T23:59:59+00:00","discovered_at":"2026-05-14T18:02:44.218924+00:00","generated_at":"2026-05-17T07:34:36.289675+00:00","sec_items":["7.01","9.01"],"event_type":"other_material","sentiment":"positive","materiality_score":0.7,"calibrated_materiality_score":0.7,"confidence":"high","headline":"Verastem reports $2.1M net product revenue from AVMAPKI FAKZYNJA launch in first 6 weeks","bullets":["AVMAPKI FAKZYNJA co-pack approved May 8, 2025 for KRAS-mutant recurrent LGSOC; $2.1M net revenue in first six weeks.","RAMP 201 trial showed 44% ORR and median DoR 3.3-31.1 months for approved combination.","RAMP 205 dose level 1 in 1L metastatic pancreatic cancer achieved 83% confirmed ORR (10/12).","VS-7375 (KRAS G12D inhibitor) Phase 1/2a trial dosed first patient in U.S.; Fast Track designation granted.","RAMP 301 confirmatory trial enrollment on track for completion by end of 2025; IDMC recommendation expected Q4 2025."],"urls":{"canonical":"https://secwatch.observer/filing/0001104659-25-088021","json":"https://secwatch.observer/filing/0001104659-25-088021.json","markdown":"https://secwatch.observer/filing/0001104659-25-088021.md","text":"https://secwatch.observer/filing/0001104659-25-088021.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1526119/000110465925088021/0001104659-25-088021-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1526119/000110465925088021/tm2525447d1_8k.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-05-17T07:34:36.289675+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}