---
schema_version: "secwatch.filing_event.v1"
accession: "0001104659-25-096658"
form_type: "8-K"
ticker: "RNAZ"
cik: "0001829635"
company_name: "Transcode Therapeutics, Inc."
filed_at: "2025-10-03T23:59:59+00:00"
generated_at: "2026-05-17T04:48:36.246827+00:00"
event_type: "other_material"
sentiment: "neutral"
materiality_score: 0.5
calibrated_materiality_score: 0.5
confidence: "high"
source: SEC EDGAR
---

# TransCode Therapeutics amends MGH license; milestone payments doubled to $2.95M per patent family

## Summary
- Second Amendment to Exclusive Patent License Agreement with Massachusetts General Hospital, effective August 15, 2025.
- Updated timelines for pre-sales requirements for Patent Family 1 and Patent Family 2.
- Aggregate one-time milestone payments increased from $1.55M to $2.95M for each patent family.
- Individual milestone amounts for therapeutic product/process milestones also updated.

## SEC filing metadata
- accession: 0001104659-25-096658
- form_type: 8-K
- ticker: RNAZ
- cik: 0001829635
- company_name: Transcode Therapeutics, Inc.
- filed_at: 2025-10-03T23:59:59+00:00
- event_type: other_material
- sentiment: neutral
- materiality_score: 0.5
- calibrated_materiality_score: 0.5
- confidence: high
- sec_items: 1.01
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1829635/000110465925096658/0001104659-25-096658-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1829635/000110465925096658/tm2527978d1_8k.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0001104659-25-096658
- JSON: https://secwatch.observer/filing/0001104659-25-096658.json
- Plain text: https://secwatch.observer/filing/0001104659-25-096658.txt

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.