SmartKem amends private placement purchase agreement to lower price protection threshold from $4.00 to $2.75

SmartKem, Inc.

Amendment dated October 13, 2025 with holders of June 2023 private placement securities.
Section 4.12(c) of Purchase Agreement changed to lower the Lower Price Issuance trigger from $4.00 to $2.75.
Consenting holders include AIGH Investment Partners and The Hewlett Fund, holding required majority.
No other terms of the Purchase Agreement were modified; public disclosure required within one day.

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