secwatch.observer — SEC 8-K summary ====================================== Issuer: RHYTHM PHARMACEUTICALS, INC. (RYTM) CIK: 0001649904 Form: 8-K Filed at: 2025-11-04T23:59:59+00:00 Accession: 0001104659-25-105904 Event type: earnings Sentiment: neutral Materiality: 0.70 Item codes: 2.02, 9.01 LLM model: deepseek-v4-flash:cloud@v2 Rhythm Q3 IMCIVREE revenue $51.3M; net loss -$0.82/sh; PDUFA Dec 20 ------------------------------------------------------------------- - Q3 2025 IMCIVREE revenue $51.3M (+6% seq, +54% YoY); US $38.2M (+19% seq). - Net loss ($54.3M) or ($0.82)/share vs ($45.0M) or ($0.73)/share a year ago. - Cash and investments $416.1M at Sep 30, 2025, up from $320.6M at Dec 31, 2024. - Updated FY2025 non-GAAP operating expense guidance $295M-$315M excluding stock-based compensation. - PDUFA date Dec 20, 2025 for setmelanotide sNDA in acquired hypothalamic obesity; Phase 2 PWS data Q4 2025. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1649904/000110465925105904/0001104659-25-105904-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1649904/000110465925105904/rytm-20251104x8k.htm HTML page: https://secwatch.observer/filing/0001104659-25-105904 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer