earnings
confidence high
sentiment neutral
materiality 0.70
Protagonist Q3 net loss $39.3M (-$0.62); cash $678.8M; icotrokinra filed, rusfertide NDA expected Q4
Protagonist Therapeutics, Inc
2025-Q3 EPS reported
-$1.35
revenue$38,579,000
- Net loss of $39.3M ($0.62 diluted EPS loss) vs $33.2M loss in Q3 2024.
- Cash $678.8M, up from $559.2M at year-end 2024; provides runway through at least end 2028.
- Icotrokinra NDA submitted to FDA (July) and EMA (September) for moderate-to-severe plaque psoriasis.
- Rusfertide granted FDA Breakthrough Therapy designation; Phase 3 VERIFY 52-week data at ASH Dec 2025; NDA filing expected Q4 2025.
- First patient dosed in Phase 1 for oral IL-17 antagonist PN-881.