secwatch / observer

8-K filed January 6, 2026, 6:59 PM ET ticker RNAZ CIK 0001829635

other material confidence high sentiment positive materiality 0.70

TransCode publishes preclinical data showing TTX-MC138 improves survival in glioblastoma models

Transcode Therapeutics, Inc.

Study in Journal of Functional Biomaterials shows TTX-MC138 delivered to GBM tumors after IV injection.
TTX-MC138 induced 5-fold increase in apoptotic activity and statistically significant survival extension.
IND-enabling studies completed; TTX-MC138 already in Phase 1a for metastatic solid tumors.
Phase 2a clinical trial for TTX-MC138 anticipated to begin in first half of 2026.

item 7.01 item 9.01

Machine-readable event card

schema_version: secwatch.filing_event.v1
accession: 0001104659-26-001097
form_type: 8-K
ticker: RNAZ
cik: 0001829635
company_name: Transcode Therapeutics, Inc.
filed_at: 2026-01-06T23:59:59+00:00
discovered_at: 2026-05-14T18:02:36.416020+00:00
generated_at: 2026-05-16T11:33:19.588207+00:00
sec_items: ["7.01", "9.01"]
event_type: other_material
sentiment: positive
materiality_score: 0.7
calibrated_materiality_score: 0.7
confidence: high
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json_url: https://secwatch.observer/filing/0001104659-26-001097.json
markdown_url: https://secwatch.observer/filing/0001104659-26-001097.md
text_url: https://secwatch.observer/filing/0001104659-26-001097.txt
edgar_index_url: https://www.sec.gov/Archives/edgar/data/1829635/000110465926001097/0001104659-26-001097-index.htm
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generated_by_model: deepseek-v4-flash:cloud@v2
review_status: machine_generated
human_reviewed: false
corrected: false
correction_note: null
correction_timestamp: null
superseded_by: null

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Source: SEC EDGAR

accession 0001104659-26-001097

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