{"schema_version":"secwatch.filing_event.v1","accession":"0001104659-26-017298","form_type":"8-K","ticker":"TRAW","cik":"0001130598","company_name":"Traws Pharma, Inc.","filed_at":"2026-02-19T23:59:59+00:00","discovered_at":"2026-05-14T18:02:34.597359+00:00","generated_at":"2026-05-16T01:39:27.713382+00:00","sec_items":["8.01","9.01"],"event_type":"other_material","sentiment":"negative","materiality_score":0.65,"calibrated_materiality_score":0.65,"confidence":"high","headline":"Traws Pharma: ratutrelvir Phase 2 shows fewer AEs, faster symptom resolution; FDA hold on tivoxavir IND","bullets":["Ratutrelvir Phase 2: 10% vs 23.3% adverse events, faster symptom resolution (HR 1.31, p=0.018), no viral rebound vs PAXLOVID.","Ratutrelvir showed benefit in PAXLOVID-ineligible patients, addressing unmet need in high-risk COVID-19 population.","Tivoxavir marboxil tablet formulation showed 30% increased pre-clinical exposure, modeled 28-day monthly prophylaxis.","FDA placed US IND for tivoxavir marboxil on clinical hold due to mutagenicity concerns; formal communication by March 16, 2026."],"urls":{"canonical":"https://secwatch.observer/filing/0001104659-26-017298","json":"https://secwatch.observer/filing/0001104659-26-017298.json","markdown":"https://secwatch.observer/filing/0001104659-26-017298.md","text":"https://secwatch.observer/filing/0001104659-26-017298.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1130598/000110465926017298/0001104659-26-017298-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1130598/000110465926017298/tm266824d1_8k.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-05-16T01:39:27.713382+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}