NextCure reports FY2025 net loss of $55.8M; cash $41.8M; SIM0505 data expected Q2 2026

NextCure, Inc.

Cash, cash equivalents and marketable securities at Dec 31, 2025: $41.8M, down from $68.6M a year ago.
Net loss for FY2025: $55.8M, roughly flat vs $55.7M in FY2024; R&D expenses rose to $44.9M.
SIM0505 (CDH6 ADC) Phase 1 dose escalation data and dose optimization start in ovarian cancer both expected Q2 2026.
LNCB74 (B7-H4 ADC) Phase 1 dose escalation update anticipated in second half of 2026.
Company expects current resources to fund operations into first half of 2027 through proof-of-concept for SIM0505.

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