Annovis Bio reports FY2025 net loss $1.40/sh; Phase 3 AD trial 65% enrolled

Annovis Bio, Inc.

FY2025 net loss $1.40 basic and diluted EPS; R&D $25.2M, G&A $4.5M; cash $19.5M expected to fund into Q3 2026.
Phase 3 AD trial (NCT06709014) 65% enrolled across 83 US sites; DSMB positive recommendation at 6-month safety review.
Open-label extension PD study initiated Jan 2026; FDA positive recommendation for PD dementia study design discussions.
All patents transferred to new crystal form of buntanetap, extending IP protection to 2047.
Appointed Mark Guerin as CFO and Hui Liu as Director of Biostatistics in 2025.

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