other material
confidence high
sentiment positive
materiality 0.80
Apogee reports positive Phase 2 52-week zumilokibart data; durable maintenance with 3- and 6-month dosing
Apogee Therapeutics, Inc.
- EASI-75 maintained in 75% (3-month) and 85% (6-month) of Week 16 responders; vIGA 0/1 maintained in 86% and 78%.
- Deepening of response across all endpoints over 52 weeks in the full zumilokibart-treated population.
- Safety profile consistent with class; common TEAEs: noninfective conjunctivitis (13.4%), URTI (12.6%), nasopharyngitis (9.2%).
- Part B 16-week induction data expected Q2 2026; Phase 3 initiation in 2H 2026; potential commercial launch in 2029.