other material
confidence high
sentiment positive
materiality 0.75
Ocugen reports 31% reduction in GA lesion growth at 12 months in Phase 2 OCU410 trial; plans Phase 3 in Q3 2026
Ocugen, Inc.
- 31% reduction in GA lesion growth (medium dose) vs control at 12 months (p<0.05); 55% of treated patients had ≥30% lesion reduction.
- No OCU410-related serious adverse events; no endophthalmitis, retinal detachment, or vasculitis reported.
- 27% slower rate of ellipsoid zone loss vs control, indicating photoreceptor preservation.
- Phase 3 pivotal trial with up to 300 subjects, adaptive design >95% power, expected to start Q3 2026.