{"schema_version":"secwatch.filing_event.v1","accession":"0001104659-26-044906","form_type":"8-K","ticker":"TOVX","cik":"0000894158","company_name":"Theriva Biologics, Inc.","filed_at":"2026-04-17T23:59:59+00:00","discovered_at":"2026-05-14T18:02:33.893473+00:00","generated_at":"2026-05-15T05:40:13.061047+00:00","sec_items":["7.01","8.01","9.01"],"event_type":"other_material","sentiment":"positive","materiality_score":0.75,"calibrated_materiality_score":0.75,"confidence":"high","headline":"Theriva reports positive VIRAGE Phase 2b data for VCN-01 in pancreatic cancer at AACR 2026","bullets":["VCN-01 + gemcitabine/nab-paclitaxel improved OS and PFS vs GnP alone in metastatic pancreatic cancer patients.","Later-emerging, higher magnitude, more durable responses observed; benefit maintained across subgroups including liver metastases.","Patients receiving a second VCN-01 dose showed greater OS and PFS benefit.","CEO reported alignment with FDA and EMA on proposed pivotal Phase 3 trial; planning study of more frequent VCN-01 dosing.","Data presented at AACR 2026 (poster CT162) on April 20, 2026."],"urls":{"canonical":"https://secwatch.observer/filing/0001104659-26-044906","json":"https://secwatch.observer/filing/0001104659-26-044906.json","markdown":"https://secwatch.observer/filing/0001104659-26-044906.md","text":"https://secwatch.observer/filing/0001104659-26-044906.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/894158/000110465926044906/0001104659-26-044906-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/894158/000110465926044906/tm2612012d1_8k.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-05-15T05:40:13.061047+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}