earnings
confidence high
sentiment negative
materiality 0.75
Bicycle Therapeutics Q1 2026 net loss $60.8M, restructures, cuts 30% staff
BICYCLE THERAPEUTICS PLC
2026-Q1 EPS reported
-$0.87
revenue$887,000
- Net loss $60.8M ($0.87/sh) flat YoY; collaboration revenue dropped to $0.9M from $10.0M.
- Cash $559.5M at March 31, 2026; expects runway into 2030 after cost cuts.
- Workforce reduced ~30%; annual operating expenses expected to drop ~50%.
- Duravelo-2 (zelenectide) converted to randomized Phase 2; Duravelo-3/4 trials discontinued.
- Phase 2 trial of nuzefatide in pancreatic cancer started; first patient dosed April 2026.