other material
confidence high
sentiment positive
materiality 0.70
Century Therapeutics presents preclinical data for CNTY-813; glucose control >8 months, IND on track for Q4 2026
Century Therapeutics, Inc.
- CNTY-813 maintained glucose control for >8 months in diabetic mouse models without immunosuppression.
- No tumorigenesis observed in >140 mice with >1 billion cells infused over 3 months follow-up.
- Allo-Evasion 5.0 edits provided protection from NK cells, antibody-mediated phagocytosis, and maintained insulin secretion in humanized mouse model.
- Phase 1 manufacturing process established; consistent product quality across 11 samples from GMP Master Cell Bank.
- IND submission on track for Q4 2026; initial clinical data expected in 2H 2027.