{"schema_version":"secwatch.filing_event.v1","accession":"0001104659-26-095905","form_type":"8-K","ticker":"PMN","cik":"0001374339","company_name":"ProMIS Neurosciences Inc.","filed_at":"2026-08-13T20:07:03+00:00","discovered_at":"2026-08-13T20:09:04.456747+00:00","generated_at":"2026-08-13T20:09:12.453749+00:00","sec_items":["2.02","9.01"],"event_type":"earnings","sentiment":"positive","materiality_score":0.8,"calibrated_materiality_score":0.8,"confidence":"high","headline":"ProMIS Q2 net loss $11.7M; PRECISE-AD interim shows no ARIA-E, biomarker declines","bullets":["Q2 2026 net loss $11.7M ($1.28/share) vs $10.1M ($7.26/share) in Q2 2025.","Cash and short-term investments $53.4M at June 30, 2026, up from $6.1M at Dec 31, 2025; $70.1M net proceeds from Jan 2026 private placement.","PRECISE-AD interim (136 patients): zero ARIA-E cases; 4.4% total ARIA (all mild ARIA-H); plasma pTau217 -15%, CSF MTBR-tau243 -13.3% in blinded pooled analysis.","Expects unblinded 12-month topline data (cognitive outcomes) in Q1 2027; cash runway through 2027.","Pipeline: PMN267 (TDP-43) and PMN442 (alpha-synuclein) advancing toward IND-enabling studies."],"urls":{"canonical":"https://secwatch.observer/filing/0001104659-26-095905","json":"https://secwatch.observer/filing/0001104659-26-095905.json","markdown":"https://secwatch.observer/filing/0001104659-26-095905.md","text":"https://secwatch.observer/filing/0001104659-26-095905.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1374339/000110465926095905/0001104659-26-095905-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1374339/000110465926095905/pmn-20260813x8k.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-08-13T20:09:12.453749+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}