secwatch.observer — SEC 8-K summary ====================================== Issuer: ProMIS Neurosciences Inc. (PMN) CIK: 0001374339 Form: 8-K Filed at: 2026-08-13T20:07:03+00:00 Accession: 0001104659-26-095905 Event type: earnings Sentiment: positive Materiality: 0.80 Item codes: 2.02, 9.01 LLM model: deepseek-v4-flash:cloud@v2 ProMIS Q2 net loss $11.7M; PRECISE-AD interim shows no ARIA-E, biomarker declines -------------------------------------------------------------------------------- - Q2 2026 net loss $11.7M ($1.28/share) vs $10.1M ($7.26/share) in Q2 2025. - Cash and short-term investments $53.4M at June 30, 2026, up from $6.1M at Dec 31, 2025; $70.1M net proceeds from Jan 2026 private placement. - PRECISE-AD interim (136 patients): zero ARIA-E cases; 4.4% total ARIA (all mild ARIA-H); plasma pTau217 -15%, CSF MTBR-tau243 -13.3% in blinded pooled analysis. - Expects unblinded 12-month topline data (cognitive outcomes) in Q1 2027; cash runway through 2027. - Pipeline: PMN267 (TDP-43) and PMN442 (alpha-synuclein) advancing toward IND-enabling studies. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1374339/000110465926095905/0001104659-26-095905-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1374339/000110465926095905/pmn-20260813x8k.htm HTML page: https://secwatch.observer/filing/0001104659-26-095905 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer