other material
confidence high
sentiment negative
materiality 0.80
MacroGenics discontinues vobra duo dosing in TAMARACK Phase 2 mCRPC study on IDMC safety recommendation
MACROGENICS INC
- IDMC recommended stopping dosing for remaining participants; most had received 8-12 cycles.
- Emerging adverse events from prolonged exposure cited; participants continue safety and survival follow-up.
- Primary endpoint 6-month rPFS data to be presented at ESMO Congress September 2024.
- Company will not hold Q2 2024 earnings call; financial results release expected August 6.
- Investor conference call planned after ESMO presentation to discuss next steps for vobra duo.