{"schema_version":"secwatch.filing_event.v1","accession":"0001140361-22-026165","form_type":"8-K","ticker":"IONS","cik":"0000874015","company_name":"IONIS PHARMACEUTICALS INC","filed_at":"2022-07-18T23:59:59+00:00","discovered_at":"2026-05-14T18:03:58.378837+00:00","generated_at":"2026-06-24T13:46:24.720036+00:00","sec_items":["5.02"],"event_type":"leadership","sentiment":"neutral","materiality_score":0.35,"calibrated_materiality_score":0.35,"confidence":"high","headline":"Ionis board member Frederick Muto retires after 21 years of service","bullets":["Frederick Muto retired from the Ionis Board of Directors effective July 15, 2022.","Muto served on the Audit, Compensation, Nominating/Governance/Review, and Finance Committees.","He had been a board member for over 21 years, providing exemplary service.","No replacement has been announced; committees will be adjusted accordingly."],"urls":{"canonical":"https://secwatch.observer/filing/0001140361-22-026165","json":"https://secwatch.observer/filing/0001140361-22-026165.json","markdown":"https://secwatch.observer/filing/0001140361-22-026165.md","text":"https://secwatch.observer/filing/0001140361-22-026165.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/874015/000114036122026165/0001140361-22-026165-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/874015/000114036122026165/brhc10039716_8k.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-06-24T13:46:24.720036+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[{"claim_id":"0107b3acab","claim":"Frederick Muto retired as Member of the Board of Directors at IONIS PHARMACEUTICALS INC.","evidence_excerpt":"On July 15, 2022, Frederick Muto, a member of the Board of Directors (“ Board ”) of Ionis Pharmaceuticals, Inc. (the “ Company ”), notified the Company that he is retiring from the Company’s Board effective July 15, 2022.","evidence_source":"SEC 8-K Item 5.02","evidence_url":"https://www.sec.gov/Archives/edgar/data/874015/000114036122026165/0001140361-22-026165-index.htm","confidence":1.0,"family_label":"Executive change","details":[{"label":"Action","value":"retired"},{"label":"Role","value":"Member of the Board of Directors"}],"fact_type":"executive_change"}],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}