---
schema_version: "secwatch.filing_event.v1"
accession: "0001140361-22-026165"
form_type: "8-K"
ticker: "IONS"
cik: "0000874015"
company_name: "IONIS PHARMACEUTICALS INC"
filed_at: "2022-07-18T23:59:59+00:00"
generated_at: "2026-06-24T13:46:24.720036+00:00"
event_type: "leadership"
sentiment: "neutral"
materiality_score: 0.35
calibrated_materiality_score: 0.35
confidence: "high"
source: SEC EDGAR
---

# Ionis board member Frederick Muto retires after 21 years of service

## Summary
- Frederick Muto retired from the Ionis Board of Directors effective July 15, 2022.
- Muto served on the Audit, Compensation, Nominating/Governance/Review, and Finance Committees.
- He had been a board member for over 21 years, providing exemplary service.
- No replacement has been announced; committees will be adjusted accordingly.

## SEC filing metadata
- accession: 0001140361-22-026165
- form_type: 8-K
- ticker: IONS
- cik: 0000874015
- company_name: IONIS PHARMACEUTICALS INC
- filed_at: 2022-07-18T23:59:59+00:00
- event_type: leadership
- sentiment: neutral
- materiality_score: 0.35
- calibrated_materiality_score: 0.35
- confidence: high
- sec_items: 5.02
- EDGAR index: https://www.sec.gov/Archives/edgar/data/874015/000114036122026165/0001140361-22-026165-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/874015/000114036122026165/brhc10039716_8k.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0001140361-22-026165
- JSON: https://secwatch.observer/filing/0001140361-22-026165.json
- Plain text: https://secwatch.observer/filing/0001140361-22-026165.txt

## Key facts
- Executive change
  Frederick Muto retired as Member of the Board of Directors at IONIS PHARMACEUTICALS INC.
  - Action: retired
  - Role: Member of the Board of Directors
  source text: On July 15, 2022, Frederick Muto, a member of the Board of Directors (“ Board ”) of Ionis Pharmaceuticals, Inc. (the “ Company ”), notified the Company that he is retiring from the Company’s Board effective July 15, 2022.
  evidence_url: https://www.sec.gov/Archives/edgar/data/874015/000114036122026165/0001140361-22-026165-index.htm

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.