secwatch.observer — SEC 8-K summary ====================================== Issuer: Tectonic Therapeutic, Inc. (TECX) CIK: 0001681087 Form: 8-K Filed at: 2022-08-09T23:59:59+00:00 Accession: 0001140361-22-028807 Event type: earnings Sentiment: neutral Materiality: 0.50 Item codes: 2.02, 9.01 LLM model: deepseek-v4-flash:cloud@v2 AVROBIO reports Q2 2022 net loss of $28.1M, cash runway into Q1 2024 -------------------------------------------------------------------- - Net loss of $28.1M in Q2 2022 vs $31.4M in Q2 2021; R&D expenses $18.9M, down from $22.5M. - Cash and equivalents $132.4M as of June 30, 2022, down from $189.6M at Dec 31, 2021; runway into Q1 2024. - All five patients in Phase 1/2 cystinosis trial remain off oral cysteamine post gene therapy. - FDA Orphan Drug Designation granted for AVR-RD-05 in Hunter syndrome; CTA authorization expected 2H 2022. - Plan to engage with regulators on cystinosis and Gaucher type 3 clinical strategies in 2H 2022. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1681087/000114036122028807/0001140361-22-028807-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1681087/000114036122028807/brhc10040479_8k.htm HTML page: https://secwatch.observer/filing/0001140361-22-028807 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer