{"schema_version":"secwatch.filing_event.v1","accession":"0001140361-23-023332","form_type":"8-K","ticker":"INSM","cik":"0001104506","company_name":"INSMED Inc","filed_at":"2023-05-08T23:59:59+00:00","discovered_at":"2026-05-14T18:03:37.953747+00:00","generated_at":"2026-06-15T12:12:52.936947+00:00","sec_items":["7.01","9.01"],"event_type":"other_material","sentiment":"positive","materiality_score":0.7,"calibrated_materiality_score":0.7,"confidence":"high","headline":"Insmed unveils four new research platforms; targets 6 INDs by 2025; DMD gene therapy trial in 2023","bullets":["Gene therapy with targeted AAV delivery; DMD clinical trial to start 2023, muscle biopsy data expected H1 2024.","RNA end-joining (REJ) technology targets Stargardt disease; IND submission expected by end of 2024.","Protein deimmunization platform (DbD) using AI to enable redosable gene therapy and therapeutic proteins.","Proprietary algae-based manufacturing platform for AAV capsid production; $500K investment from CureDuchenne Ventures.","Expects at least six IND applications across platforms by end of 2025."],"urls":{"canonical":"https://secwatch.observer/filing/0001140361-23-023332","json":"https://secwatch.observer/filing/0001140361-23-023332.json","markdown":"https://secwatch.observer/filing/0001140361-23-023332.md","text":"https://secwatch.observer/filing/0001140361-23-023332.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1104506/000114036123023332/0001140361-23-023332-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1104506/000114036123023332/brhc20052589_8k.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-06-15T12:12:52.936947+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}