secwatch.observer — SEC 8-K summary ====================================== Issuer: Tectonic Therapeutic, Inc. (TECX) CIK: 0001681087 Form: 8-K Filed at: 2023-05-11T23:59:59+00:00 Accession: 0001140361-23-024002 Event type: earnings Sentiment: neutral Materiality: 0.60 Item codes: 2.02, 9.01 LLM model: deepseek-v4-flash:cloud@v2 AVROBIO Q1 net loss $25.0M, cash $72.3M; appoints interim CEO; GD3 trial on track -------------------------------------------------------------------------------- - Net loss of $25.0M for Q1 2023 vs $29.8M in Q1 2022; R&D expenses $17.3M, G&A $7.9M. - Cash and equivalents $72.3M as of March 31, 2023; expected runway into Q1 2024. - Plan to initiate registrational Phase 2/3 trial for Gaucher disease type 3 in H2 2023, subject to regulatory alignment. - Appointed CFO Erik Ostrowski as interim CEO, succeeding Geoff MacKay; board searching for permanent CEO. - Collaborator-sponsored Phase 1/2 trial for Hunter syndrome (MPS-II) initiated. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1681087/000114036123024002/0001140361-23-024002-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1681087/000114036123024002/brhc20052752_8k.htm HTML page: https://secwatch.observer/filing/0001140361-23-024002 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer