---
schema_version: "secwatch.filing_event.v1"
accession: "0001140361-23-051195"
form_type: "8-K"
ticker: "GYRE"
cik: "0001124105"
company_name: "GYRE THERAPEUTICS, INC."
filed_at: "2023-11-02T23:59:59+00:00"
generated_at: "2026-06-08T23:23:57.277276+00:00"
event_type: "other_material"
sentiment: "neutral"
materiality_score: 0.6
calibrated_materiality_score: 0.6
confidence: "high"
source: SEC EDGAR
---

# Gyre Therapeutics dismisses auditor EisnerAmper, engages Grant Thornton; CEO and CFO exit

## Summary
- EisnerAmper dismissed as auditor; Grant Thornton Zhitong engaged as new independent registered public accounting firm.
- CEO Nassim Usman ceased as officer effective Oct 30, 2023; remains director; receives 12-month salary severance plus accelerated vesting.
- Interim CFO Seline Miller ceased as officer effective Oct 30, 2023; receives 9-month salary severance plus accelerated vesting.
- EisnerAmper’s prior reports included going-concern emphasis paragraphs related to convertible preferred stock cash settlement feature.

## SEC filing metadata
- accession: 0001140361-23-051195
- form_type: 8-K
- ticker: GYRE
- cik: 0001124105
- company_name: GYRE THERAPEUTICS, INC.
- filed_at: 2023-11-02T23:59:59+00:00
- event_type: other_material
- sentiment: neutral
- materiality_score: 0.6
- calibrated_materiality_score: 0.6
- confidence: high
- sec_items: 4.01, 5.02, 9.01
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1124105/000114036123051195/0001140361-23-051195-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1124105/000114036123051195/ny20009756x13_8k.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0001140361-23-051195
- JSON: https://secwatch.observer/filing/0001140361-23-051195.json
- Plain text: https://secwatch.observer/filing/0001140361-23-051195.txt

## Key facts
- Auditor Changes
  GYRE THERAPEUTICS, INC. dismissed EisnerAmper LLP as its auditor.
  - Action: dismissal
  - Auditor: EisnerAmper LLP
  - Successor: Grant Thornton Zhitong Certified Public Accountants LLP
  source text: (a) Dismissal of Independent Registered Public Accounting Firm Prior to the Closing Date, EisnerAmper LLP (“EisnerAmper”) served as the independent registered public accounting firm of Catalyst. On the Closing Date, following the completion of Catalyst’s audit for the year ended December 31, 2022 and the subsequent interim periods through September 30, 2023, which consisted only of the accounts of Catalyst, and the filing of Catalyst’s Annual Report on Form 10-K for the year ended December 31, 2022 and Catalyst’s Quarterly Reports on Form 10-Q for the quarters ended March 31, 2023, June 30, 2023 and September 30, 2023, the Audit Committee (the “Audit Committee”) of Gyre’s board of directors dismissed EisnerAmper as Gyre’s independent registered public accounting firm.
  evidence_url: https://www.sec.gov/Archives/edgar/data/1124105/000114036123051195/0001140361-23-051195-index.htm
- Auditor Changes
  GYRE THERAPEUTICS, INC. engaged Grant Thornton Zhitong Certified Public Accountants LLP as its auditor.
  - Action: engagement
  - Auditor: Grant Thornton Zhitong Certified Public Accountants LLP
  source text: (b) Engagement of Independent Registered Public Accounting Firm On the Closing Date, the Audit Committee engaged Grant Thornton Zhitong Certified Public Accountants LLP (“Grant Thornton”) as Gyre’s independent registered public accounting firm.
  evidence_url: https://www.sec.gov/Archives/edgar/data/1124105/000114036123051195/0001140361-23-051195-index.htm
- Executive change
  Nassim Usman departed as President and Chief Executive Officer at GYRE THERAPEUTICS, INC..
  - Action: ceased to be an officer
  - Role: President and Chief Executive Officer
  source text: Nassim Usman, Ph.D., Catalyst’s President and Chief Executive Officer, ceased to be an officer of Gyre
  evidence_url: https://www.sec.gov/Archives/edgar/data/1124105/000114036123051195/0001140361-23-051195-index.htm
- Executive change
  Seline Miller departed as Interim Chief Financial Officer at GYRE THERAPEUTICS, INC..
  - Action: ceased to be an officer
  - Role: Interim Chief Financial Officer
  source text: Seline Miller, Catalyst’s Interim Chief Financial Officer, ceased to be an officer of Gyre
  evidence_url: https://www.sec.gov/Archives/edgar/data/1124105/000114036123051195/0001140361-23-051195-index.htm

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.