---
schema_version: "secwatch.filing_event.v1"
accession: "0001140361-24-010288"
form_type: "8-K"
ticker: "IONS"
cik: "0000874015"
company_name: "IONIS PHARMACEUTICALS INC"
filed_at: "2024-02-29T23:59:59+00:00"
generated_at: "2026-06-05T07:41:53.382957+00:00"
event_type: "leadership"
sentiment: "neutral"
materiality_score: 0.6
calibrated_materiality_score: 0.6
confidence: "high"
source: SEC EDGAR
---

# Ionis announces Kyle Jenné returns as EVP Commercial; Onaiza Cadoret-Manier departs

## Summary
- Kyle Jenné rejoins as executive vice president, commercial, effective Feb 29, 2024.
- Onaiza Cadoret-Manier, EVP chief global product strategy and operations officer, leaves for another opportunity.
- Cadoret-Manier will remain full-time through March 15, 2024, then serve as advisor.
- Advisory agreement pays $12,500/month through Sep 2024, then $6,250/month through Jan 10, 2025.

## SEC filing metadata
- accession: 0001140361-24-010288
- form_type: 8-K
- ticker: IONS
- cik: 0000874015
- company_name: IONIS PHARMACEUTICALS INC
- filed_at: 2024-02-29T23:59:59+00:00
- event_type: leadership
- sentiment: neutral
- materiality_score: 0.6
- calibrated_materiality_score: 0.6
- confidence: high
- sec_items: 5.02, 1.01, 9.01
- EDGAR index: https://www.sec.gov/Archives/edgar/data/874015/000114036124010288/0001140361-24-010288-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/874015/000114036124010288/ef20022767_8k.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0001140361-24-010288
- JSON: https://secwatch.observer/filing/0001140361-24-010288.json
- Plain text: https://secwatch.observer/filing/0001140361-24-010288.txt

## Key facts
- Executive change
  Kyle Jenné was appointed as executive vice president, commercial at IONIS PHARMACEUTICALS INC.
  - Action: rejoined
  - Role: executive vice president, commercial
  source text: Kyle Jenné has rejoined Ionis as executive vice president, commercial
  evidence_url: https://www.sec.gov/Archives/edgar/data/874015/000114036124010288/0001140361-24-010288-index.htm
- Executive change
  Onaiza Cadoret-Manier departed as executive vice president, chief global product strategy and operations officer at IONIS PHARMACEUTICALS INC.
  - Action: leaving
  - Role: executive vice president, chief global product strategy and operations officer
  source text: Onaiza Cadoret-Manier, executive vice president, chief global product strategy and operations officer, is leaving the company to pursue another opportunity.
  evidence_url: https://www.sec.gov/Archives/edgar/data/874015/000114036124010288/0001140361-24-010288-index.htm

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.