---
schema_version: "secwatch.filing_event.v1"
accession: "0001140361-24-036404"
form_type: "8-K"
ticker: "GYRE"
cik: "0001124105"
company_name: "GYRE THERAPEUTICS, INC."
filed_at: "2024-08-08T23:59:59+00:00"
generated_at: "2026-05-31T10:41:01.201028+00:00"
event_type: "leadership"
sentiment: "neutral"
materiality_score: 0.5
calibrated_materiality_score: 0.5
confidence: "high"
source: SEC EDGAR
---

# Gyre Therapeutics appoints David M. Epstein, Ph.D. to Board of Directors

## Summary
- David Epstein appointed as Class II director effective Aug 6, 2024; serves on Audit and Compensation Committees.
- Epstein co-founded Black Diamond Therapeutics (BDTX) and PairX Bio; former CSO of OSI Pharmaceuticals.
- Rodney Nussbaum appointed as Chair of Audit Committee on same date.

## SEC filing metadata
- accession: 0001140361-24-036404
- form_type: 8-K
- ticker: GYRE
- cik: 0001124105
- company_name: GYRE THERAPEUTICS, INC.
- filed_at: 2024-08-08T23:59:59+00:00
- event_type: leadership
- sentiment: neutral
- materiality_score: 0.5
- calibrated_materiality_score: 0.5
- confidence: high
- sec_items: 5.02, 7.01, 8.01, 9.01
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1124105/000114036124036404/0001140361-24-036404-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1124105/000114036124036404/ef20033805_8k.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0001140361-24-036404
- JSON: https://secwatch.observer/filing/0001140361-24-036404.json
- Plain text: https://secwatch.observer/filing/0001140361-24-036404.txt

## Key facts
- Executive change
  David Epstein was appointed as Class II director at GYRE THERAPEUTICS, INC..
  - Action: appointed
  - Role: Class II director
  source text: the Board of Directors (the “Board”) of Gyre Therapeutics, Inc. (the “Company”) appointed David Epstein, Ph.D. as a Class II director to serve until the Company’s 2026 Annual Meeting of Stockholders and until his successor is duly elected and qualified.
  evidence_url: https://www.sec.gov/Archives/edgar/data/1124105/000114036124036404/0001140361-24-036404-index.htm

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.