{"schema_version":"secwatch.filing_event.v1","accession":"0001140361-24-037428","form_type":"8-K","ticker":"SIGA","cik":"0001010086","company_name":"SIGA TECHNOLOGIES INC","filed_at":"2024-08-15T23:59:59+00:00","discovered_at":"2026-05-14T18:03:11.866620+00:00","generated_at":"2026-05-31T08:56:13.702517+00:00","sec_items":["8.01","9.01"],"event_type":"other_material","sentiment":"neutral","materiality_score":0.75,"calibrated_materiality_score":0.75,"confidence":"high","headline":"SIGA's tecovirimat misses primary endpoint in PALM 007 mpox trial; shows benefit in subgroups","bullets":["PALM 007 did not meet primary endpoint of statistically significant improvement in time to lesion resolution.","Tecovirimat showed clinical benefit vs. placebo in patients treated ≤7 days from symptom onset and those with ≥100 lesions.","Safety profile comparable to placebo; consistent with prior studies over 15 years.","Four additional randomized trials (STOMP, UNITY, Platinum-CAN, EPOXI) are ongoing.","Trial hospitalized all patients, which may have reduced measured benefit vs. real-world settings."],"urls":{"canonical":"https://secwatch.observer/filing/0001140361-24-037428","json":"https://secwatch.observer/filing/0001140361-24-037428.json","markdown":"https://secwatch.observer/filing/0001140361-24-037428.md","text":"https://secwatch.observer/filing/0001140361-24-037428.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1010086/000114036124037428/0001140361-24-037428-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1010086/000114036124037428/ef20034039_8k.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-05-31T08:56:13.702517+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}