other material
confidence high
sentiment positive
materiality 0.80
PDS Biotech reports updated VERSATILE-002 trial data: mOS 30 months, ORR 36%
PDS Biotechnology Corp
- Median overall survival 30 months vs published 12-18 months for pembrolizumab alone.
- Objective response rate 36% (19/53); disease control rate 77% (41/53).
- 21% of patients (11/53) had 90-100% tumor shrinkage; 9% (5/53) complete response.
- Phase 3 VERSATILE-003 trial comparing combo vs pembrolizumab monotherapy planned to start in 2024.
- Treatment well tolerated; Grade ≥3 AEs in 9 patients (Grade 3 n=8, Grade 4 n=1).