---
schema_version: "secwatch.filing_event.v1"
accession: "0001140361-25-014376"
form_type: "8-K"
ticker: "INSM"
cik: "0001104506"
company_name: "INSMED Inc"
filed_at: "2025-04-17T23:59:59+00:00"
generated_at: "2026-05-23T11:30:24.270288+00:00"
event_type: "leadership"
sentiment: "neutral"
materiality_score: 0.4
calibrated_materiality_score: 0.4
confidence: "high"
source: SEC EDGAR
---

# Insmed CCO J. Drayton Wise resigns effective immediately for medical reasons; stays as consultant

## Summary
- J. Drayton Wise resigned as Chief Commercial Officer effective April 16, 2025, for personal and medical reasons, unrelated to operations.
- He will provide consulting services through December 31, 2025, with automatic two three-month extensions unless mutually terminated.
- Consulting fee: $30,000/month during initial period; $20,000/month during extensions. Outstanding equity awards continue to vest.
- No replacement named; Wise will support transition under a consulting agreement. Options exercisable for 3 months post-service or original 10-year expiry.

## SEC filing metadata
- accession: 0001140361-25-014376
- form_type: 8-K
- ticker: INSM
- cik: 0001104506
- company_name: INSMED Inc
- filed_at: 2025-04-17T23:59:59+00:00
- event_type: leadership
- sentiment: neutral
- materiality_score: 0.4
- calibrated_materiality_score: 0.4
- confidence: high
- sec_items: 5.02
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1104506/000114036125014376/0001140361-25-014376-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1104506/000114036125014376/ef20047566_8k.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0001140361-25-014376
- JSON: https://secwatch.observer/filing/0001140361-25-014376.json
- Plain text: https://secwatch.observer/filing/0001140361-25-014376.txt

## Key facts
- Executive change
  J. Drayton Wise resigned as Chief Commercial Officer at INSMED Inc.
  - Action: resigned
  - Role: Chief Commercial Officer
  source text: On April 16, 2025, J. Drayton Wise notified Insmed Incorporated (the “Company”) of his decision to resign from his position as the Company’s Chief Commercial Officer for personal and medical reasons, effective immediately.
  evidence_url: https://www.sec.gov/Archives/edgar/data/1104506/000114036125014376/0001140361-25-014376-index.htm

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.