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confidence high
sentiment positive
materiality 0.80
PDS Biotech reports 29.5-month median OS in low PD-L1 head and neck cancer cohort
PDS Biotechnology Corp
- Median overall survival (mOS) of 29.5 months in CPS 1-19 cohort from VERSATILE-002 Phase 2 trial.
- Published mOS for Keytruda monotherapy was 10.8 months; for Keytruda plus chemo 12.3 months.
- Approximately 60% of trial patients (n=32) had low PD-L1 expression, a historically difficult-to-treat subset.
- Data suggests PDS0101 + Keytruda may eliminate need for chemotherapy in this population.
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