other material
confidence high
sentiment positive
materiality 0.70
Opus Genetics details five IRD gene therapy programs; four data readouts expected in 2027, cash runway to 2029
Opus Genetics, Inc.
- OPGx-RDH12 enters clinical testing in Q4 2026; OPGx-MERTK Q1 2027; OPGx-RHO H2 2027.
- OPGx-LCA5 Phase 3 dosing expected Q4 2026; OPGx-BEST1 topline data from Cohort 1 due September 2026.
- Four clinical data readouts from across the pipeline expected in 2027.
- Cash runway into 2029 expected to fund multiple clinical inflection points and potential product approvals.
- Global IRD prevalence estimates provided: RDH12 ~30,900, MERTK ~21,960, RHO ~30,200, LCA5 ~3,240, BEST1 ~21,800 patients.