secwatch.observer — SEC 8-K summary ====================================== Issuer: Edgewise Therapeutics, Inc. (EWTX) CIK: 0001710072 Form: 8-K Filed at: 2022-02-24T23:59:59+00:00 Accession: 0001157523-22-000251 Event type: earnings Sentiment: positive Materiality: 0.75 Item codes: 2.02, 9.01 LLM model: deepseek-v4-flash:cloud@v2 Edgewise reports Q4 2021 net loss $12.7M, cash $281M; EDG-5506 Phase 1b positive -------------------------------------------------------------------------------- - Net loss Q4 2021 $12.7M ($0.26/share); full year net loss $42.8M ($1.14/share). - Cash, equivalents & marketable securities $281M as of Dec 31, 2021. - Phase 1b EDG-5506 in BMD: CK reduced 71%, TNNI2 reduced 83%; well-tolerated. - Phase 2 trials planned: BMD in H1 2022, DMD in H2 2022; ARCH open-label study ongoing. - R&D expenses $32.2M in 2021 (vs $15.0M in 2020); G&A $11.0M (vs $2.2M). Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1710072/000115752322000251/0001157523-22-000251-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1710072/000115752322000251/a52584668.htm HTML page: https://secwatch.observer/filing/0001157523-22-000251 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer