other material
confidence high
sentiment positive
materiality 0.75
Aldeyra reports positive Phase 2 data for ADX-2191 in retinitis pigmentosa
Aldeyra Therapeutics, Inc.
- Statistically significant improvement in best corrected visual acuity (P<0.0001) and low-light visual acuity (P=0.0001).
- Perimetry showed improved macular sensitivity (P<0.0001) and dark-adapted peripheral sensitivity (P<0.0001).
- Electroretinography time to response improved (P=0.02); no safety concerns identified.
- All 8 patients completed trial; ADX-2191 well tolerated with no serious adverse events.
- Company plans to discuss Phase 2/3 trial design with regulatory authorities.