---
schema_version: "secwatch.filing_event.v1"
accession: "0001157523-23-001660"
form_type: "8-K"
ticker: "SRRK"
cik: "0001727196"
company_name: "Scholar Rock Holding Corp"
filed_at: "2023-11-07T23:59:59+00:00"
generated_at: "2026-06-08T16:29:49.050506+00:00"
event_type: "earnings"
sentiment: "positive"
materiality_score: 0.65
calibrated_materiality_score: 0.65
confidence: "high"
source: SEC EDGAR
---

# Scholar Rock Q3 net loss $42.4M; SAPPHIRE enrollment complete, topline Q4 2024

## Summary
- Net loss $42.4M (vs $43.3M YoY); no revenue; cash $218.6M + $92.5M Oct offering extends runway into H2 2025.
- Completed enrollment of Phase 3 SAPPHIRE trial for apitegromab in SMA; topline data expected Q4 2024.
- Expanding into cardiometabolic with SRK-439; plans Phase 2 trial with apitegromab + GLP-1 RA in 2024.
- Phase 1 DRAGON trial of SRK-181 showed 21.4% ORR in ccRCC; enrollment completion in Dec 2023.
- Completed $98M public offering in October 2023; proceeds support pipeline expansion.

## SEC filing metadata
- accession: 0001157523-23-001660
- form_type: 8-K
- ticker: SRRK
- cik: 0001727196
- company_name: Scholar Rock Holding Corp
- filed_at: 2023-11-07T23:59:59+00:00
- event_type: earnings
- sentiment: positive
- materiality_score: 0.65
- calibrated_materiality_score: 0.65
- confidence: high
- sec_items: 2.02, 8.01, 9.01
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1727196/000115752323001660/0001157523-23-001660-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1727196/000115752323001660/a53761938.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0001157523-23-001660
- JSON: https://secwatch.observer/filing/0001157523-23-001660.json
- Plain text: https://secwatch.observer/filing/0001157523-23-001660.txt

## Key facts
- Earnings Releases
  Scholar Rock Holding Corp reported third quarter ended September 30, 2023 results: net income $42.4 million.
  - Period: third quarter ended September 30, 2023
  - Net income: $42.4 million
  - Result: reported results
  source text: For the quarter ended September 30, 2023, net loss was $42.4 million compared to a net loss of $43.3 million for the quarter ended September 30, 2022.
  evidence_url: https://www.sec.gov/Archives/edgar/data/1727196/000115752323001660/0001157523-23-001660-index.htm

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.