earnings
confidence high
sentiment positive
materiality 0.80
Alnylam Q4 net product rev $346M, FY $1.24B (+39%); FY24 guide $1.4-1.5B; HELIOS-B readout late June/early July
ALNYLAM PHARMACEUTICALS, INC.
2023-FY EPS reported
-$3.52
revenue$1,828,292,000
- Q4 net product revenue $346M: ONPATTRO $79M, AMVUTTRA $175M, GIVLAARI $59M, OXLUMO $33M.
- Full year 2023 net product revenue $1.24B, up 39% YoY; GAAP net loss per share ($3.52); non-GAAP ($1.61).
- FY24 guidance: combined net product revenue $1.4B-$1.5B, plus collaboration and royalty revenue; operating expense guidance provided.
- HELIOS-B Phase 3 top-line results expected late June or early July; updated statistical analysis plan announced.
- FDA cleared Part B of ALN-APP Phase 1 study at doses up to 180 mg every six months; partial clinical hold remains for higher doses.