secwatch.observer — SEC 8-K summary ====================================== Issuer: BIOCRYST PHARMACEUTICALS INC (BCRX) CIK: 0000882796 Form: 8-K Filed at: 2023-01-09T23:59:59+00:00 Accession: 0001171843-23-000154 Event type: earnings Sentiment: positive Materiality: 0.70 Item codes: 2.02, 7.01, 9.01 LLM model: deepseek-v4-flash:cloud@v2 BioCryst prelim 2022 ORLADEYO rev $251.6M (+105% YoY); FY23 guide ≥$320M; BCX10013 data positive -------------------------------------------------------------------------------- - Prelim 2022 ORLADEYO net rev $251.6M (+105% YoY); Q4 rev $70.7M (+53% YoY). - FY2023 ORLADEYO net rev guidance no less than $320M; company expects peak sales of $1B. - Phase1 data for BCX10013 (oral Factor D inhibitor): >97% AP suppression at 110 mg single dose, safe/well-tolerated. - Advancing BCX10013 into patient studies mid-2023 for PNH and IgAN; expanding complement platform to C2 targets. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/882796/000117184323000154/0001171843-23-000154-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/882796/000117184323000154/f8k_010923.htm HTML page: https://secwatch.observer/filing/0001171843-23-000154 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer