earnings
confidence high
sentiment neutral
materiality 0.70
Aptose reports Q4 net loss $10.0M; cash runway into Q1 2024; tuspetinib expansion trial underway
Aptose Biosciences Inc.
- Q4 net loss $10.0M ($0.11/sh) vs $24.3M loss year ago; FY2022 net loss $41.8M ($0.45/sh) vs $65.4M.
- Cash and investments $47.0M at Dec 31, 2022; expects funding into Q1 2024.
- APTIVATE Phase 1/2 expansion trial for tuspetinib initiated; monotherapy and TUS/VEN combination arm enrolling.
- Tuspetinib monotherapy showed 29% CR/CRh in RAS-mutated AML patients during dose escalation.
- Luxeptinib G3 formulation shows improved bioavailability; continuous dosing ongoing.