earnings
confidence high
sentiment negative
materiality 0.60
Aptose Q1 net loss widens to $13.7M; tuspetinib doublet dosing underway
Aptose Biosciences Inc.
2023-Q1 EPS reported
-$0.15
- Net loss $13.7M ($0.15/sh) vs $11.5M ($0.12) YoY; R&D spend up to $8.8M.
- Cash and investments $35.7M; runway through March 2024.
- Tuspetinib APTIVATE trial: dose escalation/exploration complete; doublet with venetoclax dosing initiated with early blast reductions.
- Safety review: no drug-induced myelosuppression or DLTs up to 160mg/day in >70 patients.
- Anticipated FDA EOP1 meeting in Q2 2023 and clinical data presentation at EHA June 2023.