{"schema_version":"secwatch.filing_event.v1","accession":"0001171843-25-002952","form_type":"8-K","ticker":"CMPX","cik":"0001738021","company_name":"Compass Therapeutics, Inc.","filed_at":"2025-05-08T23:59:59+00:00","discovered_at":"2026-05-14T18:02:49.523764+00:00","generated_at":"2026-05-22T04:59:00.820860+00:00","sec_items":["2.02","9.01"],"event_type":"other_material","sentiment":"positive","materiality_score":0.75,"calibrated_materiality_score":0.75,"confidence":"high","headline":"Compass Therapeutics: Tovecimig meets primary endpoint in BTC trial; Q1 net loss $16.6M","bullets":["Tovecimig + paclitaxel achieved 17.1% ORR (incl. 1 complete response) vs 5.3% for paclitaxel alone (p=0.031) in Phase 2/3 BTC study.","Secondary endpoints PFS, OS, DoR analyses expected Q4 2025; pre-specified event count not yet met.","Q1 2025 net loss $16.6M ($0.12/sh), R&D $13.1M (+37% YoY), cash $113M providing runway into 2027.","CTX-10726 (PD-1 x VEGF-A) pre-IND meeting completed; IND filing expected Q4 2025.","CTX-8371 Phase 1 dose-escalation advanced to 4th cohort with no DLTs; preliminary data H2 2025."],"urls":{"canonical":"https://secwatch.observer/filing/0001171843-25-002952","json":"https://secwatch.observer/filing/0001171843-25-002952.json","markdown":"https://secwatch.observer/filing/0001171843-25-002952.md","text":"https://secwatch.observer/filing/0001171843-25-002952.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1738021/000117184325002952/0001171843-25-002952-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1738021/000117184325002952/f8k_050725.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-05-22T04:59:00.820860+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}