{"schema_version":"secwatch.filing_event.v1","accession":"0001171843-25-005181","form_type":"8-K","ticker":"CLDX","cik":"0000744218","company_name":"Celldex Therapeutics, Inc.","filed_at":"2025-08-07T23:59:59+00:00","discovered_at":"2026-05-14T18:02:46.271519+00:00","generated_at":"2026-05-17T18:38:02.197477+00:00","sec_items":["2.02","9.01"],"event_type":"earnings","sentiment":"positive","materiality_score":0.75,"calibrated_materiality_score":0.75,"confidence":"high","headline":"Celldex Q2 net loss $56.6M ($0.85/share); cash $630.3M; barzolvolimab shows durable complete response at 76 weeks","bullets":["Net loss of $56.6M versus $35.8M in Q2 2024; R&D spend rose to $54.2M on barzolvolimab trials.","Cash and securities $630.3M (down $43M QoQ); company expects runway through 2027.","Phase 2 CSU barzolvolimab: up to 41% complete response at 76 weeks (7 months off-treatment); 48% no quality-of-life impact.","Phase 3 CSU program (EMBARQ-CSU1/2) enrolling globally; Phase 2 CIndU and EoE data due in 2H 2025.","Phase 1 CDX-622 (bispecific SCF/TSLP) in healthy volunteers: Part 1 data expected 2H 2025."],"urls":{"canonical":"https://secwatch.observer/filing/0001171843-25-005181","json":"https://secwatch.observer/filing/0001171843-25-005181.json","markdown":"https://secwatch.observer/filing/0001171843-25-005181.md","text":"https://secwatch.observer/filing/0001171843-25-005181.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/744218/000117184325005181/0001171843-25-005181-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/744218/000117184325005181/f8k_080625.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-05-17T18:38:02.197477+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}