{"schema_version":"secwatch.filing_event.v1","accession":"0001171843-25-005992","form_type":"8-K","ticker":"APTOF","cik":"0000882361","company_name":"Aptose Biosciences Inc.","filed_at":"2025-09-22T23:59:59+00:00","discovered_at":"2026-05-14T18:02:46.569756+00:00","generated_at":"2026-05-17T06:03:39.399893+00:00","sec_items":["7.01","9.01"],"event_type":"debt","sentiment":"neutral","materiality_score":0.65,"calibrated_materiality_score":0.65,"confidence":"high","headline":"Aptose secures $11.9M loan from Hanmi to fund tuspetinib AML study","bullets":["Amended facility with Hanmi provides up to $11.9M in uncommitted advances through Dec 31, 2025; first advance expected soon.","Final $1.4M advance received under prior June 2025 facility, totaling $8.5M from that agreement.","Loan is a related-party transaction; Aptose relies on financial hardship exemption from formal valuation and minority approval.","Proceeds fund TUSCANY Phase 1/2 trial of tuspetinib + venetoclax + azacitidine in newly diagnosed AML patients.","Early data showed 9/10 patients responded; 100% CR/CRh at 80mg and 120mg cohorts across adverse mutations."],"urls":{"canonical":"https://secwatch.observer/filing/0001171843-25-005992","json":"https://secwatch.observer/filing/0001171843-25-005992.json","markdown":"https://secwatch.observer/filing/0001171843-25-005992.md","text":"https://secwatch.observer/filing/0001171843-25-005992.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/882361/000117184325005992/0001171843-25-005992-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/882361/000117184325005992/f8k_092225.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-05-17T06:03:39.399893+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}