other material
confidence high
sentiment positive
materiality 0.75
Edesa Biotech: paridiprubart shows 32% relative mortality reduction in AKI/ARDS patients
Edesa Biotech, Inc.
- Exploratory Phase 3 data: paridiprubart + SOC reduced 28-day mortality to 33% vs 49% placebo (p<0.005).
- MAKE30 composite endpoint incidence reduced to 41% from 53% (23% relative reduction, p<0.005).
- AKI cohort of 101 severely ill patients (90% moderate-to-severe ARDS, ~50% on ventilation/ECMO).
- Paridiprubart well tolerated; no significant differences in adverse events vs placebo.
- Data presented at ERA Congress 2026; results exploratory and require confirmatory studies.