other material
confidence high
sentiment positive
materiality 0.65
Silexion CEO letter details 2025 progress; Phase 2/3 trial in LAPC set for H1 2026
Silexion Therapeutics Corp
- SIL204 showed >90% inhibition in human cancer cell lines across 8 KRAS mutations and 5 tumor types.
- Positive regulatory feedback from Germany's BfArM on Phase 2/3 design; toxicology studies completed.
- Phase 2/3 LAPC trial initiation planned H1 2026; US IND expected H2 2026.
- Company raised over $18M in 2025 and regained Nasdaq compliance; addressable market >$30B.