regulatory
confidence high
sentiment positive
materiality 0.85
Silexion gets Israeli MoH approval for Phase 2/3 trial of SIL204 in pancreatic cancer
Silexion Therapeutics Corp
- SIL204 is a next-generation RNAi therapy targeting multiple KRAS mutations in pancreatic cancer.
- Approval follows positive preclinical anti-tumor data and completed toxicology studies.
- Human trials expected to begin in Q2 2026; also planning German application in current quarter.
- Company plans to pursue additional KRAS-driven indications including colorectal and lung cancers.