other material
confidence high
sentiment positive
materiality 0.85
IGC Pharma reports positive interim Phase 2 results for IGC-AD1 in Alzheimer's agitation
IGC Pharma, Inc.
- Cohen's d effect size at week 6=0.66, CMAI LS mean difference vs placebo=-10.45, p=0.037.
- At pre-specified week 2 endpoint, effect size=0.79, suggesting early onset of action.
- Interim results compare favorably to Brexpiprazole's Phase 3 (Cohen's d 0.35, LS mean -5.32).
- Trial ongoing (n=26 interim); final results may differ as enrollment continues in US and Canada.
- IGC-AD1 targets CB1 receptor, neuroinflammation, and inflammasome-3 pathways.