{"schema_version":"secwatch.filing_event.v1","accession":"0001193125-21-244019","form_type":"8-K","ticker":"SYBX","cik":"0001527599","company_name":"SYNLOGIC, INC.","filed_at":"2021-08-12T23:59:59+00:00","discovered_at":"2026-05-14T18:04:18.449081+00:00","generated_at":"2026-06-29T12:53:25.686112+00:00","sec_items":["2.02","9.01"],"event_type":"earnings","sentiment":"neutral","materiality_score":0.7,"calibrated_materiality_score":0.7,"confidence":"high","headline":"Synlogic Q2 2021 net loss narrows to $14.5M; PKU and Enteric Hyperoxaluria trials on track for 2H readouts","bullets":["Cash, equivalents, and investments of $115.5M as of June 30, 2021; runway into second half of 2023.","Net loss of $14.5M ($0.28/shr) vs. $15.5M ($0.44/shr) in Q2 2020; revenue of $0.2M from Roche IBD collaboration.","SYNB1618 Phase 2 PKU trial ongoing; Phase 1 of next-generation SYNB1934 initiated in July 2021.","SYNB8802 Enteric Hyperoxaluria Part B enrolling; proof-of-concept data expected in 2H 2021.","Combination arm of SYNB1891 (atezolizumab) Phase 1 in solid tumors; mature data expected by year-end."],"urls":{"canonical":"https://secwatch.observer/filing/0001193125-21-244019","json":"https://secwatch.observer/filing/0001193125-21-244019.json","markdown":"https://secwatch.observer/filing/0001193125-21-244019.md","text":"https://secwatch.observer/filing/0001193125-21-244019.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1527599/000119312521244019/0001193125-21-244019-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1527599/000119312521244019/d340812d8k.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-06-29T12:53:25.686112+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}